In vivo toxicity study of Lantana camara.
نویسندگان
چکیده
OBJECTIVE To investigate the toxicity of methanol extract of various parts (Root, Stem, Leaf, Flower and Fruit) of Lantana camara (L. Camara) in Artemia salina. METHODS The methanol extracts of L. camara were tested for in vivo brine shrimp lethality assay. RESULTS All the tested extract exhibited very low toxicity on brine shrimp larva. The results showed that the root extract was the most toxic part of L. camara and may have potential as anticancer agent. CONCLUSIONS Methanolic extract of L. camara is relatively safe on short-term exposure.
منابع مشابه
Cytotoxicity and oral acute toxicity studies of Lantana camara leaf extract.
BACKGROUND The objective of this study was to investigate the toxicity of Lantana camara methanol extract. METHODS In order to evaluate the toxicity of Lantana camara, the acute toxicity of the methanolic extract on adult mice and cytotoxicity test on Vero cell line were investigated. A fixed large dose of 2 g/kg body weight of L. camara leaf extract was administrated by a single oral gavage ...
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ورودعنوان ژورنال:
- Asian Pacific journal of tropical biomedicine
دوره 1 3 شماره
صفحات -
تاریخ انتشار 2011